Table 7. In Vitro Antiproliferative Activity of Representative Compounds.

	IC50 (μM)a
cpd	U937	K562	HEL	KG1	HL60	MDA-MB-231	PC-3	MCF-7	HCT116	A549
11e	0.33	0.79	0.20	0.39	2.11	0.24	0.33	3.47	0.37	3.39
11p	0.32	0.68	0.27	0.72	1.59	0.41	0.53	2.95	0.57	3.91
11r	0.16	0.51	0.19	0.22	1.69	0.22	0.46	2.68	0.52	2.74
11w	0.18	1.01	0.19	0.24	1.04	0.27	0.51	2.7	0.37	2.96
11y	0.34	0.89	0.16	0.47	1.68	0.15	0.29	2.32	0.22	3.27
21c	0.73	0.94	0.27	0.49	2.17	0.31	0.37	3.25	0.58	3.19
SAHA	1.45	3.24	0.49	1.59	4.26	1.72	3.57	3.78	2.81	3.9

^aAssays were performed in replicate (n ≥ 2); the SD values are <20% of the mean.