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Effect of ROME (10 μM, 24 h) on lyso-PI and LPA species in androgen-sensitive LNCaP cells. Results are expressed as the ratio ROME:control for each metabolite. P values are presented for ROME vs. control (experimental results from n = 3 cell samples for each treatment).
| Ratio of ROME : control | P value n = 3 | |
|---|---|---|
| Lyso-PI 16:0 | 218.2 | < 0.005 |
| Lyso-PI 18:0 | 30.0 | < 0.005 |
| Lyso-PI 18:1 | 22.2 | < 0.005 |
| Palmityl glucuronide | 11.2 | < 0.01 |
| LPA 16:0 | 2.4 | < 0.05 |
| LPA 16:1 | 1.4 | < 0.01 |
| LPA 18:0 | 3.6 | < 0.05 |
