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. 2012 Nov 15;3(4):839–863. doi: 10.3390/jfb3040839

Table 1.

Test methods and relative brain measures.

Test Method Measured Property ASTM Standards Measured CNS data Refs.
Magnetic Resonance Elastography Shear Modulus N/A HUMAN: Grey 5.22 kPa; [191]
White 13.6 kPa @ 100 Hz
Shear Storage/ Loss Modulus HUMAN: G' (Storage) = 1.13 kPa; [192]
G" (Loss) = 0.935 kPa @100 Hz
Shear Modulus HUMAN: 3.5 kPa @ 83.33 Hz [193,194]
G'(Storage) Grey matter = 3.1 kPa
G'(Storage) White matter = 2.7 kPa @200 Hz
Dynamic Testing Shear Storage/ Loss Modulus D4065 PRIMATE: G' = 0.6-1.1 kPa; [194]
G" = 0.35-0.6 kPa @ 9-10 Hz
Dynamic Elastic Modulus HUMAN : E' = 67 kPa; E" = 26 kPa; [195]
E*=72 kPa @ 34 Hz
PRIMATE : E' = 91 kPa; E" = 54 kPa;
E* = 105 kPa @ 31 Hz
Dynamic Storage/ Loss Modulus HUMAN: Storage: 0.39 kPa, 0.47 kPa, 0.65 kPa [196]
Loss: 0.075 kPa, 0.094 kPa, 0.190 kPa @ 0.1,
1 and 10 Hz respectively
Compression Testing Elastic Modulus D1621, D695, D575 PORCINE 5.7 kPa @ 1 s−1; [197]
11.9 kPa @ 10 s−1; 23.8 kPa @ 50 s−1
Shear ModulusMooney Rivlin Material Model BOVINE : 2.26 kPa [198]
(Equation constants for Mooney-Rivlin Model)
Elastic Modulus PORCINE: 38.5 kPa [199]
Tensile Testing Elastic Modulus D1708 PORCINE: 4.2 kPa @ .9 s−1; [197]
4.0 kPa @ 4.3 s−1; 18.6 kPa @ 25 s−1
Pressure/Volume Testing Elastic Modulus N/A PRIMATE (in vivo): 10.0-3.50 kpa [200]
Relaxation Testing Relaxation Modulus D6048 HUMAN: 6.6 kPa @ 34 Hz [196]
PRIMATE: 10.3 kPa @ 31 Hz
Indentation Testing Shear Modulus E2546 PORCINE: Grey Matter 0.74 kPa; [201]*
White Matter 1.03 kPa @ 0.1 mm/s
Elastic/Shear Modulus RAT: 13-17 day old: 3.34 kPa; [202]*
43-90 day old: 1.72 kPa
Shear modulus and Relaxtion functions PORCINE: Short Term: In vivo 1.88 kPa; [203]
In Situ 2.80 kPa; In Vitro 1.36 kPa
Long Term: In vivo 0.685 kPa;
In Situ 0.926 kPa; In Vitro 0.468 kPa
Atomic Force Microscopy Elastic/Shear Modulus E42, RAT (hippocampus): pyramidal layer: [204]
CA1 0.14 kPa; CA3 0.23 kPa
E2382 stratum radiatum: CA1 0.17 kPa;
CA3 0.31 kPa @ 3µm indentation

* It should be noted that these authors calculated Shear Modulus from indentation data per a formula derived by Lee and Radok in 1960. This value is normally calculated using dynamic or oscillatory methods. ASTM standard provides guidelines for using indentation to calculate Elastic modulus.