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(a) Structure of active site of catechol 1,2 dioxygenase highlighting the residue that define the active site pocket (PDB file from crystallographic structure in [117]); (b) The effect of reshaping by mutagenesis and SSM on model of substrate/pocket interaction; (c) The list of identified and characterized mutants for SSM on position 72 are reported in the table (related to studies published in [114]).
