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. Author manuscript; available in PMC: 2015 Apr 25.
Published in final edited form as: Circ Res. 2014 Mar 18;114(9):1398–1409. doi: 10.1161/CIRCRESAHA.114.303870

Figure 2. β-AR/PKA trigger nuclear activation of PKD.

Figure 2

(A) PKD activity measurements with targeted DKAR constructs in sarcolemmal, cytosol and nuclear compartments (n>30 myocytes, *P<0.01). (B) Representative western blot and quantification of S916 phosphorylation (~global PKD activity) in response to agonist treatment. GAPDH and PKD signals serve as loading controls.