Number of peer-reviewed manuscripts by year that have used adaptive optics systems to image the retina in one or more patients. A literature search (February 1, 2013) found 75 such papers.9, 33, 37, 43–45, 49, 58, 62, 76, 77, 79, 88–90, 95, 97–155 *=2012 includes papers from the first few weeks of 2013. We did not include papers that only referenced normal subjects.