Figure 5. The strong link between intracellular Ca²⁺ and AP shape still exist in the cAF-remodeled virtual cell.

Clamping the CaT (A) in the subsarcolemmal space to be normal (as in nSR) speeds up the initial and slows later repolarisation phases of membrane voltage (B), due to indirect changes in I_NCX (C) and I_CaL (D).