Figure 4. Cytokine expression in the bleomycin-treated skin from the wild-type (WT) and ET-1^f/f; Tie-2-Cre (+) (KO) mice.

Total RNA was extracted from the skin, and the mRNA expression levels of indicated cytokines were determined by real-time PCR. Data are expressed as the mean ± SD of six independent experiments. *P<0.05 as compared with the value in WT mice (1.0).