Table 3.
Survival outcomes by WBC risk group
| WBC risk groupa |
Univariable Analysis |
||||
|---|---|---|---|---|---|
| N | 1-yr (%), (95% CI) | 5-yr (%), (95% CI) | p-valueb | ||
|
| |||||
| OS | 0 | 937 | 73 (70,76) | 47 (44, 51) | ref |
| 1 | 91 | 46 (36, 56) | 30 (21, 40) | <0.0001 | |
| 2 | 81 | 31 (21, 41) | 15 (8, 24) | <0.0001 | |
|
| |||||
| PFS | 0 | 937 | 58 (55, 61) | 39 (36, 43) | ref |
| 1 | 91 | 35 (26, 45) | 22 (14, 31) | <0.0001 | |
| 2 | 81 | 25 (16, 34) | 14 (7, 22) | <0.0001 | |
|
| |||||
| NRM | 0 | 937 | 9 (7, 11) | 19 (17, 22) | ref |
| 1 | 91 | 24 (16, 33) | 28 (19, 37) | 0.008 | |
| 2 | 81 | 32 (22, 42) | 37 (27, 48) | 0.0005 | |
|
| |||||
| Relapse | 0 | 937 | 32 (29, 35) | 41 (38, 44) | ref |
| 1 | 91 | 41 (30, 51) | 51 (39, 61) | 0.29 | |
| 2 | 81 | 43 (32, 54) | 49 (38, 60) | 0.0005 | |
a
0: referent group; 1: low WBC during the first 3 months of HCT; 2: high WBC during the first 3 months of HCT, 3: normal WBC initially but disease progression or relapse during the first 3 months of HCT.
b
stratified by conditioning intensity