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. Author manuscript; available in PMC: 2015 Feb 3.
Published in final edited form as: Mol Pharm. 2014 Jan 6;11(2):545–559. doi: 10.1021/mp4005035

Figure 1.

Figure 1

Comparative nanoDSC traces of cationic lipid SPYRIT-7 (“lipid”) formulated with DOPE (a, b) or cholesterol (c, d) at 1:1 (a, c) and 1:2 (b, d) molar ratios, in water, in the absence (red traces) of in the presence of 5% GS SPYRIT-68 (“GS”, green traces), against the pure cationic lipid formulation (black traces). Broadening and shifting the thermal transition of the cationic lipid to lower values by addition of colipid and subsequent complete bilayer fluidification through GS addition can be observed.