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. Author manuscript; available in PMC: 2015 Feb 3.
Published in final edited form as: Mol Pharm. 2014 Jan 6;11(2):545–559. doi: 10.1021/mp4005035

Figure 4.

Figure 4

Size (panels a, b), zeta potential (panels c, d), transfection efficiency (panels e, f) and cytotoxicity (panels g, h) against NCI-H23 cell line of lipoplexes formed at a +/− charge ratio of 3 from SPYRIT-68/SPYRIT-7 (0/100 red bars, 5/95 green bars, 10/90 violet bars) cationic amphiphiles coformulated with either DOPE or cholesterol at 1:1 and 1:2 molar ratios. P values were determined by two-way ANOVA within one set of formulations (*P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001) or one-way ANOVA, comparing the value with the previous one (#P <0.05, ##P < 0.01, ###P < 0.001 and ####P < 0.0001). In the transfection efficiency experiment (e, f) one-way ANOVA was performed relative to Lipofectamine formulation (ϕP < 0.05). Only the statistical significant differences were shown.