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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Circ Heart Fail. 2014 Feb 13;7(3):479–490. doi: 10.1161/CIRCHEARTFAILURE.113.000713

Figure 6. Effects of inhibition of CnA on the enhancement of TAC-induced fibrosis and apoptosis in Murf1−/− mice.

Figure 6

Tg-ZAKI, Murf1−/−, Murf1−/−-Tg-ZAKI or NTg mice were subjected to TAC for 4 weeks. A, Apoptosis was evaluated with TUNEL staining. The right panel shows the results of the quantitative analysis. * P<0.05 (N=10–15). B, Interstitial fibrosis was evaluated with Masson’s Trichrome staining. The right panel shows the results of the quantitative analysis. * P<0.05 (N=9).