Skip to main content
. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Circ Heart Fail. 2014 Feb 13;7(3):479–490. doi: 10.1161/CIRCHEARTFAILURE.113.000713

Figure 7. Hypothetical model of MuRF1 and CnA interactions in response to pressure overload (PO) in the heart.

Figure 7

Expression of CnA is increased but that of MuRF1 is decreased in response to PO, and MuRF1 negatively regulates pathological hypertrophy in part through proteasomal degradation of CnA.