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. Author manuscript; available in PMC: 2015 May 15.
Published in final edited form as: J Immunol. 2014 Apr 18;192(10):4592–4600. doi: 10.4049/jimmunol.1302517

Table III.

KIR-Better/Best Donors Improve Outcomes for C1/x Recipients

Outcome Donor KIR Group All Transplants HLA-Matched HLA-Mismatched
N RR P N RR P N RR P
Recipient HLA C1/x LFS KIR-Neutral 865 1.00 502 1.00 363 1.00
KIR-Better/Best 354 0.78 (0.67–0.91) 0.0015 201 0.86 (0.69–1.07) 0.17 153 0.70 (0.56–0.88) 0.003
Relapse KIR-Neutral 903 1.00 521 1.00 382 1.00
KIR-Better/Best 367 0.70 (0.56–0.87) 0.0018 211 0.79(0.59–1.06) 0.11 156 0.61 (0.43–0.88) 0.008
TRM KIR-Neutral 893 1.00 516 1.00 377 1.00
KIR-Better/Best 363 0.89 (0.72–1.09) 0.26 207 1.02 (0.75–1.40) 0.90 156 0.82 (0.62–1.10) 0.19
Recipient HLA C2/C2 LFS KIR-Neutral 148 1.00 77 1.00 71 1.00
KIR-Better/Best 75 0.93 (0.63–1.37) 0.71 42 0.81 (0.45–1.43) 0.47 33 1.28 (0.67–2.45) 0.45
Relapse KIR-Neutral 152 1.00 80 1.00 72 1.00
KIR-Better/Best 80 0.80 (0.47–1.36) 0.41 43 0.64 (0.29–1.42) 0.27 37 1.20 (0.51–2.83) 0.68
TRM KIR-Neutral 150 1.00 79 1.00 71 1.00
KIR-Better/Best 78 0.94 (0.57–1.55) 0.81 42 0.89 (0.42–1.89) 0.76 37 0.98 (0.45–2.16) 0.96