Table IV.

C1/x Recipients Receiving Transplants with Mismatch at HLA-C Benefit from Enhanced Protection with KIR-Better/Best Donors

A: Transplants with Mismatch at HLA Class I or Class I and Class II vs. Mismatch at HLA Class II
	Donor KIR Group	Includes Class I Mismatch			Class II Mismatched Only
		N	RR	P	N	RR	P
LFS	KIR-Neutral	310	1.00		53	1.00
	KIR-Better/Best	131	0.69 (0.54–0.88)	0.0029	22	1.31 (0.57–3.02)	0.53
Relapse	KIR-Neutral	323	1.00		59	1.00
	KIR-Better/Best	134	0.62 (0.42–0.92)	0.019	22	1.45 (0.47–4.50)	0.52

B: HLA Class I Mismatch Transplants at HLA-C vs. HLA-A and/or HLA-B
	Donor KIR Group	HLA-C Mismatched			HLA-A,B Mismatched
		N	RR	P	N	RR	P
LFS	KIR-Neutral	185	1.00		125	1.00
	KIR-Better/Best	83	0.57 (0.40–0.79)	0.001	48	0.97 (0.63–1.49)	0.89
Relapse	KIR-Neutral	192	1.00		131	1.00
	KIR-Better/Best	85	0.54 (0.33–0.88)	0.013	49	0.68 (0.32–1.45)	0.32