Table V.

Impact of Individual Donor KIR B Genes on LFS and Relapse in C1/x Recipients

A. All Transplants
Donor KIR Group	n	RR	P	n	RR	P
		LFS			Relapse
KIR A/A	404	1.00		422	1.00
KIR B/x with 2DS2+	615	0.85 (0.73–0.99)	0.041	639	0.86 (0.69–1.06)	0.15
KIR B/x with 2DS5+	382	0.85 (0.72–1.01)	0.068	397	0.83 (0.66–1.05)	0.12
KIR B/x with 2DL2+	610	0.86 (0.74–1.00)	0.056	634	0.87 (0.70–1.07)	0.19
KIR B/x with 2DS1+	463	0.84 (0.71–0.99)	0.036	483	0.80 (0.64–1.00)	0.052
KIR B/x with 3DS1+	448	0.83 (0.70–0.98)	0.027	469	0.79 (0.63–0.99)	0.044
KIR B/x with 2DS3+	306	0.81 (0.67–0.97)	0.025	321	0.85 (0.66–1.09)	0.20
KIR B/x with 2DL5+	584	0.86 (0.74–1.01)	0.061	608	0.87 (0.71–1.08)	0.20

B. HLA Matched
Donor KIR Group	n	RR	P	n	RR	P
		LFS			Relapse
KIR A/A	233	1.00		240	1.00
KIR B/x with 2DS2+	344	0.96 (0.77–1.19)	0.71	361	1.04 (0.79–1.38)	0.77
KIR B/x with 2DS5+	221	0.96 (0.76–1.21)	0.73	231	1.04 (0.76–1.41)	0.82
KIR B/x with 2DL2+	341	0.96 (0.77–1.19)	0.70	358	1.04 (0.79–1.37)	0.79
KIR B/x with 2DS1+	274	0.96 (0.77–1.20)	0.71	287	0.98 (0.73–1.32)	0.90
KIR B/x with 3DS1+	267	0.93 (0.74–1.17)	0.54	281	0.97 (0.72–1.31)	0.86
KIR B/x with 2DS3+	178	0.97 (0.75–1.25)	0.78	189	1.07 (0.77–1.50)	0.67
KIR B/x with 2DL5+	341	0.99 (0.80–1.23)	0.95	358	1.09 (0.82–1.44)	0.55

C. HLA Mismatched
Donor KIR Group	n	RR	P	n	RR	P
		LFS			Relapse
KIR A/A	171	1.00		182	1.00
KIR B/x with 2DS2+	271	0.78 (0.62–0.99)	0.037	278	0.68 (0.49–0.95)	0.023
KIR B/x with 2DS5+	161	0.75 (0.58–0.99)	0.040	166	0.59 (0.40–0.88)	0.0090
KIR B/x with 2DL2+	269	0.80 (0.63–1.01)	0.055	276	0.70 (0.51–0.98)	0.036
KIR B/x with 2DS1+	189	0.73 (0.56–0.94)	0.015	196	0.59 (0.41–0.85)	0.0052
KIR B/x with 3DS1+	181	0.73 (0.57–0.95)	0.018	188	0.57 (0.39–0.83)	0.0038
KIR B/x with 2DS3+	128	0.65 (0.48–0.86)	0.0032	132	0.58 (0.38–0.88)	0.0098
KIR B/x with 2DL5+	243	0.75 (0.59–0.96)	0.020	250	0.63 (0.44–0.88)	0.0076