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. 2014 Apr 6;145(3):725–734. doi: 10.1007/s10549-014-2916-8

Table 6.

Sites of first disease progression following first-line therapy for HER2-positive MBC

Site at progressive disease, n (%) De novo patients (n = 327) Recurrent patients (n = 674)
Bone/breast only 103 (31.5) 174 (25.8)
Visceral 73 (22.3) 226 (33.5)
Any central nervous system 57 (17.4) 105 (15.6)
Node/local 16 (4.9) 61 (9.1)
Other sites 0 (0) 1 (0.1)

Site of first disease progression after metastatic diagnosis HER2 human epidermal growth factor receptor 2