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. 2014 May 19;14:342. doi: 10.1186/1471-2407-14-342

Table 4.

Genomic features of the mutations

A. Genome distribution of the mutations
Gene Position Repetitive sequence Structural variation Fragile site
BPTF
chr17:65850386
-
+
-
-
-
CACNB3
chr12:49220218
-
+
-
-
-
CHCHD1
chr10:75541868
-
+
-
-
-
FOXP1
chr3:71247489
-
+
-
-
-
GSTK1
chr7:142964824
-
+
-
-
-
ITGA1
chr5:52240783
-
+
-
-
-
LACRT
chr12:55028594
-
+
-
-
-
PHKG2
chr16:30767746
-
+
-
-
-
SRA1
chr5:139936828
-
+
-
-
-
CLCN4
chrX:10176455
-
+
-
-
-
LAT
chr16:29000901
-
+
-
-
-
KCTD8
chr4:44177010
-
+
-
-
-
ABLIM2
chr4:8055946
-
+
4A
5149099
8732840
PAMR1
chr11:35456266
-
+
11E
31043424
36443424
TTN
chr2:179400887
-
+
2G
169791754
182991755
UEVLD
chr11:18553971
-
-
11C
16143424
21643424
ZNF24
chr18:32919897
-
-
18A
32746002
37246002
CUL4B
chrX:119680410
-
-
-
-
-
SEMA3C
chr7:80374250
-
-
-
-
-
TBC1D22B
chr6:37280778
-
-
-
-
-
TMPRSS7
chr3:111797705
-
-
-
-
-
ZNF304
chr19:57868409
+
-
-
-
-
ZNF674
chrX:46359537
+
-
-
-
-
B. Transition/ transversion of the mutations
Wild type
Mutation
Wild type
Mutation
 
 
 
Common mutations (> = 2)
C
T
T
G
 
 
 
C
T
G
T
 
 
 
C
T
C
G
 
 
 
C
T
 
 
 
 
 
G
A
 
 
 
 
 
G
A
 
 
 
 
 
G
A
 
 
 
 
 
G
A
 
 
 
 
 
G
A
 
 
 
 
 
Individual mutations
C
T
A
T
 
 
 
G
A
A
T
 
 
 
G
A
A
C
 
 
 
G
A
G
T
 
 
 
G
A
G
T
 
 
 
 
 
C
A
 
 
 
C. Transition/Transversion ratio
Class
Transition
Transversion
Ratio
 
 
 
Total mutation
14
9
1.6
 
 
 
Common
9
3
3
 
 
 
Individual 5 6 0.8