Table 3.
Unadjusted | Adjusted* | |||||
---|---|---|---|---|---|---|
Total arterial compliance
†
|
HR |
95% CI |
P |
HR |
95% CI |
P |
Composite events |
1.14 |
1.10-1.18 |
<.0001 |
1.07 |
1.01-1.14 |
0.03 |
Cardiovascular death |
1.10 |
1.01-1.20 |
0.02 |
0.97 |
0.73-1.30 |
0.85 |
Nonfatal cardiac events |
1.15 |
1.10-1.20 |
<.0001 |
1.11 |
1.04-1.19 |
0.001 |
Nonfatal extra-cardiac vascular events |
1.10 |
1.02-1.19 |
0.02 |
0.97 |
0.74-1.28 |
0.86 |
Ascending aortic distensibility
‡
|
|
|||||
Composite events |
1.63 |
1.50-1.77 |
<.0001 |
1.18 |
0.95-1.46 |
0.08 |
Cardiovascular death |
1.49 |
1.25-1.77 |
<.0001 |
0.72 |
0.41-1.28 |
0.27 |
Nonfatal cardiac events |
1.69 |
1.52-1.87 |
<.0001 |
1.45 |
1.18-1.78 |
0.0005 |
Nonfatal extra-cardiac vascular events |
1.52 |
1.31-1.76 |
<.0001 |
1.09 |
0.76-1.57 |
0.63 |
Arch pulse wave velocity
§
|
|
|||||
Composite events |
1.23 |
1.15-1.31 |
<.0001 |
1.11 |
0.89-1.32 |
0.28 |
Cardiovascular death |
1.25 |
1.11-1.41 |
<.0001 |
0.92 |
0.63-1.33 |
0.64 |
Nonfatal cardiac events |
1.19 |
1.08-1.32 |
<.0001 |
1.00 |
0.76-1.32 |
0.97 |
Nonfatal extra-cardiac vascular events | 1.76 | 1.24-2.11 | <.0001 | 1.18 | 1.02-1.55 | 0.04 |
*adjusted for age, sex, ethnicity, systolic blood pressure, use of blood pressure medication, resting heart rate, diabetes mellitus, current smoking, body mass index, and hypercholesterolemia.
†hazard ratios per 1SD (0.46 ml/mmHg) decrease in total arterial compliance.
‡hazard ratios per 1SD (3.1 mmHg−1 × 10−3) decrease in aortic distensibility.
§hazard ratios per 1SD (3.0 m/s) increase in pulse wave velocity.