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. 2014 Apr 12;289(21):14812–14828. doi: 10.1074/jbc.M114.550574

FIGURE 1.

FIGURE 1.

Grx2 deficiency induces cardiac hypertrophy and left ventricular fibrosis in 10-week-old mice. a, heart weight. Values were normalized to femur length (g/cm). n = 4, mean ± S.E., Student's t test. b, serum hemoglobin levels. n = 6, mean ± S.E. c, histological analysis of cell size (H&E) and fibrosis (Sirius Red) in left ventricle. d, echocardiographic images of left ventricle in M-mode of mice aged 10 weeks. Left ventricular wall parameters (Tables 1 and 2) calculate left ventricular wall mass, percent fractional contraction, and ejection efficiency in mice aged 10 weeks (e) and 16 weeks (f). n = 7, mean ± S.E., Student's t test.