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Activation of tAlv-a1-pHCl by pH. A, tAlv-a1-pHCl course pH screen. B, tAlv-a1-pHCl fine pH screen. C, pH induced channel activation was fitted with a Hill equation and yielded an EC50 of 3.24 and a Hill coefficient of 2.5 for tAlv-a1-pHCl. Error bars indicate mean ± S.E. The currents measured at the indicated pH values are from between 4 and 14 oocytes.
