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. 2014 Mar 27;139(2):381–395. doi: 10.1093/toxsci/kfu052

TABLE 3. List of Genes Down-regulated in AHRRa-MO-injected Zebrafish Embryos.

Probe name Description Accession number Fold change Adjusted p-value B
A_15_P107533 Phosphodiesterase 6C, cGMP-specific, cone, alpha prime (pde6c) NM_200871 −8.09 0.000 13.30
A_15_P115980 Opsin 1 (cone pigments), short-wave-sensitive 1 (opn1sw1) NM_131319 −7.24 0.000 13.53
A_15_P114133 Phosphodiesterase 6H, cGMP-specific, cone, gamma (pde6h) NM_200785 −10.09 0.000 12.54
A_15_P117046 Opsin 1 (cone pigments), medium-wave-sensitive, 1 (opn1mw1) NM_131253 −7.35 0.000 12.35
A_15_P106879 Arrestin 3, retinal (X-arrestin) (arr3) NM_200792 −4.40 0.000 11.94
A_15_P120294 Retinal degradation slow 2 (rds2) NM_131566 −5.22 0.000 11.37
A_15_P111532 Guanine nucleotide binding protein (G protein), beta polypeptide 3 (gnb3) NM_213202 −5.58 0.000 11.16
A_15_P121399 Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 (gnat2) NM_131869 −7.08 0.000 10.98
A_15_P107383 Phosducin 2 (pdc2) NM_001025464 −3.61 0.000 10.50
A_15_P102875 Retinal degradation slow 4 (rds4) NM_131567 −5.60 0.000 10.19
A_15_P110693 Retinal degradation slow 2 (rds2) NM_131566 −3.57 0.000 10.05
A_15_P104722 Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3, like (slc25a3l), nuclear gene encoding mitochondrial protein NM_200715 −3.25 0.000 10.05
A_15_P109108 Villin 1 like (vil1l) NM_200238 −3.95 0.000 9.43
A_15_P119413 Opsin 1 (cone pigments), short-wave-sensitive 2 (opn1sw2) NM_131192 −5.59 0.000 9.17
A_15_P119429 Opsin 1 (cone pigments), long-wave-sensitive, 2 (opn1lw2) NM_001002443 −2.98 0.000 8.72
A_15_P111012 Opsin 1 (cone pigments), long-wave-sensitive, 2 (opn1lw2) NM_001002443 −3.37 0.000 8.54
A_15_P104674 Retinol binding protein 4, like (rbp4l) NM_199965 −3.26 0.000 8.48
A_15_P104664 Arrestin 3, retinal (X-arrestin), like (arr3l) NM_001002405 −5.21 0.000 8.32
A_15_P103714 Guanylate cyclase activator 1C (guca1c) NM_194393 −2.79 0.000 7.59
A_15_P106371 XM_678537 carboxypeptidase B1 (tissue) isoform 1 (Danio rerio) (exp = −1; wgp = 0; cg = 0), complete TC311008 −2.81 0.000 7.47
A_15_P115516 Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3, like (slc25a3l), nuclear gene encoding mitochondrial protein NM_200715 −2.82 0.000 7.11
A_15_P108311 Chymotrypsinogen B2 precursor (zgc:112160) NM_001017724 −4.05 0.000 6.98
A_15_P116791 Calcium/calmodulin-dependent protein kinase IG (camk1g) NM_199966 −2.26 0.000 6.56
A_15_P109678 Calcium binding protein 5b (cabp5b) (zgc:109977) NM_001020732 −2.64 0.000 6.47
A_15_P119059 Guanylate kinase 1 (guk1) NM_200724 −2.52 0.000 6.42
A_15_P108795 Retinaldehyde binding protein 1b (rlbp1b) NM_205690 −2.99 0.000 6.34
A_15_P102721 Chitinase, acidic.2 precursor (zgc:55941) NM_213249 −2.53 0.000 6.21
A_15_P100788 SH3-domain GRB2-like 2 (sh3gl2) NM_201116 −2.08 0.001 5.83
A_15_P117814 Trypsin (try) NM_131708 −3.13 0.001 5.30
A_15_P113799 Chymotrypsinogen B1 (ctrb1) NM_212618 −3.05 0.002 5.05
A_15_P115606 Q6PBU3_BRARE (Q6PBU3) Stathmin-like 4, complete NM_213401 −2.07 0.002 4.86
A_15_P112264 Group-specific component (vitamin D binding protein) (zgc:92753) NM_001002568 −2.86 0.002 4.70
A_15_P113364 Glycogenin, like (gygl) NM_001002062 −2.08 0.002 4.57
A_15_P113940 Uncharacterized protein LOC445282 precursor (zgc:92041) NM_001003737 −4.09 0.002 4.53
A_15_P107695 Fatty acid binding protein 10, liver basic (fabp10) NM_152960 −2.58 0.003 4.15
A_15_P110245 Unknown −2.64 0.004 3.81
A_15_P110192 Pyrophosphatase (inorganic) (pp) NM_200733 −2.00 0.004 3.83
A_15_P110812 Trypsin-1-like (zgc:66382) NM_199605 NM_199605 −2.98 0.004 3.78
A_15_P115802 Cathepsin L, 1 b (ctsl1b) NM_131198 −2.79 0.004 3.69
A_15_P118837 3-Oxoacid CoA transferase 1a (oxct1a) NM_001007291 −2.28 0.004 3.66
A_15_P115815 G-Protein-coupled receptor kinase 7a (grk7a) NM_001031841 −2.18 0.004 3.70
A_15_P112986 Solute carrier family 31 (copper transporters), member 1 (slc31a1) NM_205717 −2.05 0.004 3.67
A_15_P114820 Recoverin (rcv1) NM_199964 −2.12 0.004 3.60
A_15_P113750 Serum/glucocorticoid regulated kinase 1-like (si:ch211–195b13.1) NM_001077302 −2.21 0.004 3.53
A_15_P100752 Alanine-glyoxylate aminotransferase, like (agxtl) NM_001002331 −3.16 0.005 3.35
A_15_P120962 ATPase, Na+/K+ transporting, beta 2b polypeptide (atp1b2b) NM_131838 −2.07 0.005 3.36
A_15_P112975 Transmembrane 4 L six family member 4 (tm4sf4) (zgc:92479) NM_001003489 −2.21 0.005 3.27
A_15_P103143 Uncharacterized protein LOC327506 (zgc:56085) NM_199816 −2.75 0.006 3.15
A_15_P112053 Retinal outer segment membrane protein 1b (zgc:56548) NM_201014 −2.73 0.006 3.17
A_15_P120424 Lysozyme [source: RefSeq_peptide; Acc:NP_631919] ENSDART00000080549 −2.04 0.006 3.15
A_15_P105587 Prominin 1 b (prom1b) NM_198071 −2.28 0.006 2.98
A_15_P108560 Internexin neuronal intermediate filament protein, alpha a (inaa) NM_001144784 −2.28 0.007 2.89
A_15_P116896 Guanine nucleotide binding protein (G protein), beta 5 (gnb5) NM_200746 −2.07 0.007 2.85
A_15_P102378 Glutamate decarboxylase 1 (gad1) NM_194419 −2.50 0.007 2.80
A_15_P104848 Tubulin polymerization-promoting protein family member 3 (tppp3) NM_201335 −2.35 0.007 2.80
A_15_P118058 Unknown −3.22 0.008 2.67
A_15_P103108 Trypsin-1-like (zgc:66382) NM_199605 CF595078 −2.10 0.008 2.69
A_15_P120202 SH3-domain GRB2-like 2 (sh3gl2) NM_201116 −2.18 0.008 2.65
A_15_P112659 Transferrin-a (tfa) NM_001015057 −2.17 0.009 2.45
A_15_P118533 D. rerio cDNA clone IMAGE: 7395709 BC092811 −2.37 0.010 2.25
A_15_P120388 Chymotrypsinogen B1 (ctrb1) NM_212618 −2.07 0.015 1.83
A_15_P121355 Uncharacterized protein LOC393832 (zgc:77748) NM_200858 −2.21 0.016 1.73
A_15_P113063 Similar to cathepsin L (MGC174155) NM_001103118 −2.15 0.017 1.59
A_15_P114615 Guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 (ENSDART00000024136) (gngt2a) XM_001336994 −2.13 0.017 1.57
A_15_P103612 Family with sequence similarity 3, member C (fam3c) NM_212725 −2.02 0.017 1.56
A_15_P118740 Oxysterol binding protein-like 7 (osbpl7) NM_001005927 −2.02 0.019 1.37
A_15_P101585 Heat shock protein, alpha-crystallin-related, b11 (hspb11) NM_001099427 −2.28 0.023 1.10
A_15_P110869 Urate oxidase (uox) NM_001002332 −2.19 0.026 0.87
A_15_P110951 PREDICTED: D. rerio similar to myosin heavy chain fast skeletal type 2 (LOC100002040) XM_001339170 −2.14 0.028 0.73
A_15_P121427 Amylase, alpha 2A; pancreatic (amy2a) NM_213011 −2.37 0.032 0.54
A_15_P112046 Probable protein BRICK1 (zgc:86903) NP_001002097 −2.04 0.034 0.40
A_15_P111425 Amylase, alpha 2A; pancreatic (amy2a) NM_213011 −2.22 0.038 0.25
A_15_P114488 Q4SAD3_TETNG (Q4SAD3) chromosome 19 SCAF14691, whole genome shotgun sequence, partial (43%) TC324157 −2.00 0.039 0.17
A_15_P106129 Ependymin (epd) NM_131005 −2.01 0.041 0.07
A_15_P119722 Trypsin-1-like (zgc:66382) NM_199605 CF595078 −2.23 0.048 −0.15

Note. Probe name corresponds to the Agilent probe ID. Fold change values, adjusted p-value and B-statistic are based on the statistical analysis. Only genes that showed ≥2-fold change are shown in the table. The full list of differentially expressed genes is given Supplementary table 2.