Table 3.
Corpus callosum and interhemispheric tract measurements in both preterm groups and controls
| Controls | Preterm |
ANCOVA [1] |
ANCOVA [2] |
|||||
|---|---|---|---|---|---|---|---|---|
| Unimpaired language | Impaired language | Covariates: age, sex, ICV/age, sex | Post hoc: preterm groups | Covariates: age, sex, total WM | Post hoc: preterm groups | |||
| Total corpus callosum | Area (mm2) | 709 (104) | 671 (112) | 500 (95)*** | F(2,72) = 20.5, P < 0.0001 | P < 0.0001 | F(2,73) = 10.3, P < 0.0001 | P < 0.0001 |
| FA | 0.53 (0.04) | 0.51 (0.07) | 0.46 (0.08)*** | F(2,74) = 7.3, P = 0.001 | P = 0.006 | - | - | |
| Segment of corpus callosum (area, mm2) | I | 18.7 (3.4) | 18.8 (3.3) | 14.8 (2.5)** | F(2,72) = 9.9, P < 0.0001 | P < 0.0001 | F(2,73) = 6.1, P = 0.004 | P = 0.004 |
| II | 19.1 (2.7) | 17.3 (3.2) | 13.3 (3.1)*** | F(2,72) = 16.3, P < 0.0001 | P < 0.0001 | F(2,73) = 4.7, P = 0.012 | P = 0.004 | |
| III | 7.6 (1.5) | 7.3 (2.0) | 5.3 (1.4)*** | F(2,72) = 8.7, P < 0.0001 | P < 0.0001 | F(2,73) = 3.2, P = 0.045 | P = 0.017 | |
| IV | 3.6 (1.5) | 3.3 (0.8) | 2.3 (0.9)** | F(2,72) = 6.7, P = 0.002 | P = 0.004 | F(2,73) = 2.6, P = 0.085 | P = 0.04 | |
| V | 21.9 (4.2) | 20.7 (4.4) | 14.4 (4.0)*** | F(2,72) = 16.5, P < 0.0001 | P < 0.0001 | F(2,73) = 6.9, P = 0.002 | P < 0.0001 | |
| Occipital transcallosal fibres | Volume (cm3) | 39.5 (7.1) | 37.7 (11.4) | 35.9 (15.9) | F(2,70) = 0.6, P = 0.570 | P = 0.575 | F(2,70) = 0.8, P = 0.446 | P = 0.541 |
| FA | 0.30 (0.03) | 0.30 (0.02) | 0.29 (0.04) | F(2,72) = 0.7, P = 0.509 | P = 0.251 | - | - | |
| Parietal transcallosal fibres | Volume (cm3) | 62.4 (16.5) | 56.6 (24.9) | 53.0 (18.7) | F(2,70) = 1.3, P = 0.271 | P = 0.582 | F(2,70) = 0.6, P = 0.581 | P = 0.413 |
| FA | 0.29 (0.03) | 0.29 (0.03) | 0.28 (0.03) | F(2,72) = 1.2, P = 0.304 | P = 0.18 | - | - | |
| Temporal transcallosal fibres | Volume (cm3) | 12.5 (9.5) | 12.2 (10.5) | 2.3 (3.0)*** | F(2,70) = 8.6, P < 0.0001 | P = 0.001 | F(2,70) = 7.9, P = 0.001 | P = 0.001 |
| FA | 0.37 (0.04) | 0.37 (0.08) | 0.38 (0.11) | F(2,72) = 0.04, P = 0.959 | P = 0.86 | - | - | |
Table displays mean unadjusted values and standard deviation in parenthesis. Value in bold are significant.
Different from controls **P ≤ 0.01, ***P ≤ 0.001, - = not performed.
FA = fractional anisotropy; ICV = intracranial volume; WM = white matter volume.