Table 5.

OR for coronary heart disease in relation to the joint presence of a high (>5) or low GPS (≤5) and lipids.

GPS	CHD risk factor	With CHD, n	CHD-free, n	OR (95%CI)	P value*	OR (95%CI)	P value†
≤5	Total cholesterol<5.20 mmol/L	59	179	0.51(0.24–1.10)	0.086	0.49(0.23–1.06)	0.068
	Total cholesterol≥5.20 mmol/L	45	166	0.43(0.20–0.92)	0.029	0.41(0.19–0.87)	0.021
>5	Total cholesterol<5.20 mmol/L	56	87	1.89(0.89–4.01)	0.097	1.59(0.73–3.43)	0.241
	Total cholesterol≥5.20 mmol/L	37	92	1(Reference)		1(Reference)
≤5	LDL cholesterol<2.60 mmol/L	33	123	0.23(0.09–0.56)	0.001	0.24(0.10–0.59)	0.002
	LDL cholesterol≥2.60 mmol/L	72	220	0.47(0.25–0.87)	0.017	0.47(0.25–0.89)	0.021
>5	LDL cholesterol<2.60 mmol/L	35	50	1.15(0.50–2.62)	0.745	1.06(0.45–2.49)	0.902
	LDL cholesterol≥2.60 mmol/L	57	131	1(Reference)		1(Reference)
≤5	HDL cholesterol≥1.04 mmol/L	50	116	0.17(0.07–0.43)	<0.001	0.18(0.07–0.45)	<0.001
	HDL cholesterol<1.04 mmol/L	54	229	0.39(0.21–0.72)	0.003	0.40(0.21–0.76)	0.005
>5	HDL cholesterol≥1.04 mmol/L	42	65	0.69(0.32–1.52)	0.362	0.69(0.31–1.57)	0.381
	HDL cholesterol<1.04 mmol/L	51	114	1(Reference)		1(Reference)
≤5	Triglycerides<1.65 mmol/L	56	207	0.63(0.30–1.31)	0.212	0.57(0.27–1.20)	0.140
	Triglycerides≥1.65 mmol/L	48	138	0.19(0.07–0.50)	0.001	0.18(0.07–0.47)	0.001
>5	Triglycerides<1.65 mmol/L	42	104	1.38(0.66–2.91)	0.394	1.15(0.54–2.45)	0.720
	Triglycerides≥1.65 mmol/L	51	75	1(Reference)		1(Reference)

^*Adjusted for age, sex, body mass index, physical activity, smoking habit, alcohol consumption, diabetes, and prior medications.

^†Further adjustment for population admixture.