Table 1.

Patient-based analysis: intraobserver and interobserver variability in the sum longest diameter (SLD) of target lesions for baseline measurements and for the percent change at the first follow-up scan.

Intraobserver variability of SLD (Two measurements by Radiologist 1)
	CCC (95%CI)	Mean relative difference(%)	95% limits of agreement(%)
Baseline (n=71)	0.9984 (0.9974–0.9990)	−0.365	−7.90, 7.17
%change on follow-up (n=69)	0.9747 (0.9597–0.9841)	0.282	−7.30, 7.86
Interobserver variability of SLD (Measurements by Radiologist 1 vs. Radiologist 2)
	CCC (95%CI)	Mean relative difference(%)	95% limits of agreement(%)
Baseline (n=71)	0.9875 (0.9800–0.9921)	−0.173	−17.0, 16.6
%change on follow-up (n=69)	0.8969 (0.8389–0.9348)	−0.444	−16.3, 15.4