Table 3.
Odds ratios for IHPS in infants according to total cholesterol levels in plasma from umbilical cord blood.
| Cases | Controls | OR (95% CI) | P | P nonlinearity | |||
|---|---|---|---|---|---|---|---|
|
| |||||||
| n | Mean | n | Mean | ||||
| All | 46 | 65.22 | 189 | 75.25 | 0.02b | 0.07d | |
| Quartile 1 (cholesterol level ≤ 58)a | 20 | 48.20 | 46 | 51.00 | 1.00 (reference) | ||
| Quartile 2 (58 < cholesterol level ≤ 70) | 10 | 64.20 | 48 | 65.33 | 0.54 (0.23–1.30) | ||
| Quartile 3 (70 < cholesterol level ≤ 84) | 11 | 76.55 | 45 | 78.31 | 0.51 (0.21–1.21) | ||
| Quartile 4 (84 < cholesterol level) | 5 | 110.4 | 50 | 104.32 | 0.21 (0.07–0.63) | ||
| OR per 10 mg/dL increase | – | – | – | – | 0.77 (0.64–0.92) | 0.005c | |
a
Quartiles of total cholesterol (mg/dL).
b
Omnibus test for no difference in ORs between quartiles using conditional logistic regression.
c
Test for no change in risk per 10 mg/dL increase using conditional logistic regression.
d
Test for nonlinearity using conditional logistic regression and comparing a model including cholesterol as a quadratic term to a model only including cholesterol as a linear term.