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. Author manuscript; available in PMC: 2014 May 23.
Published in final edited form as: Prog Mol Biol Transl Sci. 2011;101:1–21. doi: 10.1016/B978-0-12-387685-0.00001-9

Fig. 4.

Fig. 4

MBD containing proteins. (A) Domain architecture of known and putative proteins containing a MBD domain. (B) Model of the reactions that regulate H3K9 methylation by SUV39H1 or SETDB1. Recognition of methylated CpGs by the methyl-CpG domain of MBD1 directs methylation of H3K9me3. The “?” refers to the interactions need to be experimentally verified.