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. 2013 Feb 20;33(8):3668–3678. doi: 10.1523/JNEUROSCI.2921-12.2013

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Copyright © 2013 the authors 0270-6474/13/333668-11$15.00/0

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Figure 7. — NNDs between Ca_v2.1 and BK or SK2 channels. A, B, NNDs between BK (A) or SK2 (B) and Ca_v2.1 particles within the P-face IMP clusters were analyzed. In both cases, median of NND was quite small (∼40 nm) suggesting calcium nanodomain formation. These NNDs (Real) were compared with randomly distributed NNDs (Random) generated using the same numbers of BK or SK2 particles same IMP cluster areas. The real NNDs were significantly smaller than the random NNDs for Ca_v2.1 and SK2 (p = 0.019, Man–Whitney U test, p = 0.001, Kolmogorov–Smirnov test) but not for Ca_v2.1 and BK.