Table 5.
Two-Part Model for Adjusted Inpatient/Emergency Department Costs
| Medication-specific medical costs | Mean adjusted costs, $ (inpatient/emergency department) | Difference in costs, $ | 95% Confidence interval | |
|---|---|---|---|---|
| Lower costs, $ | Upper costs, $ | |||
| All-cause costs | ||||
| Aripiprazole | 295 | 0 | 0 | 0 |
| Olanzapine | 377 | 82 | −25 | 189 |
| Quetiapine | 421a | 126 | 37 | 214 |
| Risperidone | 388a | 94 | 1 | 190 |
| Ziprasidone | 538a | 243 | 115 | 376 |
| Mental health–related costs | ||||
| Aripiprazole | 215 | 0 | 0 | 0 |
| Olanzapine | 247 | 31 | −43 | 107 |
| Quetiapine | 283 | 67 | −3 | 138 |
| Risperidone | 264 | 49 | −26 | 115 |
| Ziprasidone | 368a | 153 | 41 | 259 |
P <.05 versus aripiprazole.
Costs are reported per treated patient per month in 2008 US dollars. Estimates are reported after controlling for age, sex, year of index prescription, Charlson comorbidity index, diabetes, hyperlipidemia, glucose and lipid testing, baseline hospitalization rate, and use of mood stabilizers.