Table 2.

Outcomes and Patient-Rated Instruments

Instrument name	Purpose	Scale	Score rangea
Clinician-rated instruments
mAIMS (modified Abnormal Involuntary Movement Scale)5,13	Assess the severity of abnormal movements in 6 different areas of the body	5-point scale, with ratings from 0–4 (absent, minimal, mild, moderate, severe), with higher scores indicating more severe abnormal movements	0–24: Mild = 0–12 Moderate = 13–18 Severe = 19+
UPDRS (Unified Parkinson's Disease Rating Scale)5,12	Assess the severity of Parkinson's disease symptoms using a 5-point scale with ratings from 0 (normal) to 4 (severe), with higher scores indicating greater disability from Parkinson's disease	The UPDRS is made up of the following sections5,12: Part I: Evaluation of mentation, behavior, and mood Part II: Self-evaluation of ADLs Part III: Clinician-scored motor evaluation Part IV: Complications of therapy Modified Hoehn and Yahr staging of severity of Parkinson's disease Schwab and England ADLs scale These are evaluated by interview and clinical observation Some sections require multiple grades assigned to each extremity	This study included only select questions from Part IV (Complications of therapy, questions 32 and 33)
Patient-rated instruments
PDYS-26 (Parkinson Disease Dyskinesia 26-item Scale)5	Quantify the impact of dyskinesia on ADLs during the past week	5-point scale, where 0 = not at all and 4 = activity impossible	0–104: Mild = 0–26 Moderate = 27–52 Severe = 53+
PDQ-39 (39-item Parkinson's Disease Questionnaire)14,15	Measure health status, covering 8 aspects of quality of life	5-point scale, where 0 = never and 4 = always	0–156: Mild = 0–39 Moderate = 40–78 Severe = 79+

^aMild, moderate, and severe ranges were determined by multiplying the number of questions by the score assigned to that severity (eg, in the PDYS-26, a moderate severity score = 2; therefore 2 * 26 = 52) to determine the maximum score for the moderate range.

ADLs indicates activities of daily living.