Table 5.
One-Way Sensitivity Analyses
| Model parameter | Sensitivity range | ICER range, $ thousands |
|---|---|---|
| Episode of care costsa | Base case to +$5000 | $39.5 to $58.5 |
| Major AE taperb | Base case to year 2 | $39.5 to $47.8 |
| AMI disutilities | −0.24 to −0.12 | $39.5 to $40.7 |
| Stroke disutilities | −0.5 to −0.3 | $39.5 to $41.8 |
| Cost of deathc | Base case to $0 | $39.5 to $45.1 |
| Death probabilities | 0% to 10% | $39.5 to $59.3 |
| Discount rate | 0% to 5% | $33.5 to $43.1 |
a
Base case, $58,194 for pVAD episode of care costs.
b
Base case, nonfatal major adverse cardiovascular and cerebrovascular event probabilities equilibrate at year 5.
c
Base case, $23,774 for cost of death.
AMI indicates acute myocardial infarction; ICER, incremental cost-effectiveness ratio; AE, adverse event; pVAD, percutaneous ventricular assist device.