Table 1.

The Model's Assumptions

Variables	rtPA	Placebo	Source
rtPA cost, $	2750	—	Hospital billing
Consult physician cost, $	467	—	Hospital billing
ICU cost, $	1206	—	Hospital billing
Intracranial hemorrhage rate, %	0.0645	0.01	NINDS
Died in hospital, %	0.074	0.101	NINDS
Discharged home, %	0.46	0.36	NINDS
Rehabilitation to nursing home, %	0.18	0.18	NINDS
Death multiplier	1.65	1.65	NINDS
Annual restroke, %	0.052	0.052	NINDS
Recurrent stroke death, %	0.18	0.18	NINDS
Hospital days, N	10.9	12.4	NINDS
Daily hospital cost, $	2984	2984	HCUP
Rehabilitation days, N	20	20	NINDS
Daily rehabilitation cost, $	1652	1652	HCUP
Home health days, N	10	10	NINDS
Daily home health cost, $	349	349	HCUP
ICH added cost, $	7002	7002	HCUP
Annual nursing home cost, $	62,218	62,218	HCUP
Subsequent stroke cost, $	64,096	64,096	HCUP
Utilities R0	0.9	0.9	Fagan model
Utilities R1	0.8	0.8	Fagan model
Utilities R2	0.46	0.46	Fagan model
Utilities R3	0.34	0.34	Fagan model
Utilities R4	0.3	0.3	Fagan model
Utilities R5	0.01	0.01	Reflective of national policy

HCUP indicates Healthcare Cost and Utilization Project; ICH, intracerebral hemorrhage; ICU, intensive care unit; NINDS, National Institute of Neurological Disorders and Stroke; rtPA, recombinant tissue plasminogen activator.

Sources: South Carolina Universal Billing 92 Form discharge data; HCUP nationwide inpatient sample 2010. www.hcup-us.ahrq.gov/db/nation/nis/nisdbdocumentation.jsp; 2009 and 2010 HCUP state inpatient data for South Carolina, State Inpatient Databases. www.hcup-us.ahrq.gov/db/state/siddbdocumentation.jsp; NINDS. Clinical research tool kit. www.ninds.nih.gov/research/clinical_research/toolkit/common_data_elements.htm.