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. 2014 Jun 6;87(2):187–197.

Table 1. Summary of Evidence, by Outcome (abstracted from “Table. Summary of Evidence, by Outcome” (Bright TJ, et al.; 2012).

Outcome Evidence Strength Studies (Quality Rating), n Meta-Analysis Result for Outcomes (95% CI) Studies Included in the Meta- Analysis, n Other Substantial Findings
Length of stay Low 6 (6 good) RR, 0.96 (0.88–1.05) favoring CDSS 5 Limited evidence that CDSSs that automatically delivered system-initiated recommendations to providers were effective or demonstrated a trend toward reducing length of stay
Morbidity Moderate 22 (13 good, 7 fair, 2 poor) RR, 0.88 (0.80–0.96) favoring CDSS 16 Modest evidence from academic and community inpatient and ambulatory settings that locally developed CDSSs that automatically delivered system-initiated recommendations to providers synchronously at the point of care were effective or demonstrated a trend toward reducing patient morbidity
Mortality Low 7 (6 good, 1 fair) OR, 0.79 (0.54–1.15) favoring CDSS 6 Limited evidence that CDSSs integrated in CPOE or EHR systems that automatically delivered system-initiated recommendations to providers were effective or demonstrated a trend toward reducing patient mortality
Adverse events Low 5 (3 good, 1 fair, 1 poor) RR, 1.01 (0.90–1.14) favoring control 5 Limited evidence from academic settings that CDSSs that delivered recommendations to providers synchronously at the point of care demonstrated an effect on reducing or preventing adverse events
Health care process measures. Recommended preventive care service ordered or completed High 43 (20 good, 16 fair, 7 poor) OR, 1.42 (1.27–1.58) favoring CDSS 25 Strong evidence from studies conducted in academic, VA, and community inpatient and ambulatory settings that locally and commercially developed CDSSs that automatically delivered system-initiated recommendations to providers synchronously at the point of care and did not require a mandatory clinician response were effective at improving the appropriate ordering of preventive care procedures
Recommended clinical study ordered or completed Moderate 29 (16 good, 9 fair, 4 poor) OR, 1.72 (1.47–2.00) favoring CDSS 20 Modest evidence from studies conducted in academic and community inpatient and ambulatory settings that CDSSs integrated in CPOE or EHR systems and locally and commercially developed CDSSs that automatically delivered system-initiated recommendations to providers synchronously at the point of care and did not require a mandatory clinician response were effective at improving the appropriate ordering of clinical studies
Recommended treatment ordered or prescribed High 67 (35 good, 24 fair, 8 poor) OR, 1.57 (1.35–1.82) favoring CDSS 46 Strong evidence from academic, community, and VA inpatient and ambulatory settings that locally and commercially developed CDSSs integrated in CPOE or EHR systems that automatically delivered system-initiated recommendations to providers synchronously at the point of care and did not require a mandatory clinician response were effective at improving appropriate treatment ordering or prescribing