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. 2012 Oct-Dec;24(4):407–414. doi: 10.1590/S0103-507X2012000400019

Table 7.

Managing the major complications related to intraosseous access.(11)

Complications Treatments
Extravasation Remove the device, elevate the limb, and apply a cold compress to the puncture site
Osteomyelitis Remove the device within 24 hours. Initiate antibiotic therapy (as prescribed by the physician) to treat the osteomyelitis
Compartment syndrome Remove the device, elevate the limb, apply a cold compress to the puncture site, and consult the surgeon (fasciotomy and removal of necrotic tissue are required in severe cases)
Fat embolism No specific treatment (no cases have been reported in the literature for pediatric patients)