Table 1.
Clinical and laboratory features of studied patients
| Features | All patients | Low base-excess | High base-excess | p value |
| (N=84) | (N=48) | (N=36) | ||
| Age (years) | 50.21 (17.40) | 51.02 (18.70) | 49.13 (15.64) | 0.61 |
| Sex, male | 49 (58) | 25 (52) | 20 (55) | 0.75 |
| SAPS3 | 52.50 (41.75-64.75) | 55 (43.25-68.25) | 51 (41.75-61.25) | 0.51 |
| SOFA at admission | 5 (2-9) | 7 (3-9) | 3.5 (2-6.5) | <0.01 |
| Sepsis | 43 (51) | 32 (66) | 11 (30) | <0.01 |
| ICU mortality | 20 (23) | 13 (27) | 7 (19) | 0.41 |
| Hospital mortality | 26 (30) | 18 (37) | 8 (22) | 0.13 |
| pH | 7.38 (7.33-7.41) | 7.36 (7.29-7.40) | 7.40 (7.38-7.41) | <0.01 |
| BE (mEq/L) | -2.4 (-4.87-0.75) | -4.55 (-8.47-3.2) | -0.3 (-1.12-2.65) | <0.01 |
| HCO3- (mEq/L) | 21.8 (19-24) | 19.65 (17.45-21.50) | 24.4 (23.28-27.22) | <0.01 |
| PCO2 (mmHg) | 37.1 (32.45-44) | 34.15 (29.98-39.78) | 41 (37.32-46.02) | <0.01 |
| Na (mEq/L) | 139 (136-143.2) | 138 (135.8-143) | 140 (137-144) | 0.11 |
| Cl (mEq/L) | 104 (104-108.2) | 104.5 (101.8-108) | 104 (100-109) | 0.88 |
| Mg (mg/dL) | 1.95 (1.68-2.22) | 1.97 (1.68-2.13) | 1.93 (1.68-2.32) | 0.73 |
| Ca (mg/dL) | 5 (4-5) | 4.5 (4-5) | 5.0 (4.75-5.0) | 0.01 |
| P (mg/dL) | 3.4 (2.77-4.95) | 3.65 (2.67-5.10) | 3.30 (2.8-4.3) | 0.57 |
| Albumin (mg/dL) | 3.0 (2.3-3.5) | 2.8 (2.1-3.2) | 3.35 (2.87-3.62) | <0.01 |
| Lactate (mmol/L) | 1.56 (1.11-2.48) | 1.83 (1.27-2.61) | 1.38 (1.11-1.80) | 0.03 |
| AG (mEq/L) | 16.50 (13.92-19.12) | 17.35 (16.05-20.98) | 15.15 (12.85-16.70) | <0.01 |
| AGCAPL (mEq/L) | 6.69 (4.34-9.34) | 8.68 (6.34-10.52) | 4.95 (2.69-6.61) | <0.01 |
| SIG (mEq/L) | 8.12 (5.79-10.92) | 9.82 (7.76-12.32) | 5.82 (3.73-7.41) | <0.01 |
| SIDa (mEq/L) | 40.90 (37.13-43.86) | 39.24 (36.37-41.31) | 43.26 (40.26-45.74) | 0.01 |
| SIDe (mEq/L) | 32.09 (28.45-35.90) | 29.11 (26.61-31.18) | 36.29 (34.10-39.40) | <0.01 |
SAPS3 - Simplified Acute Physiology Score; SOFA - Sepsis Related Organ Failure Assessment; ICU - intensive care unit; BE - base-excess; AG - anion gap; AGCAPL - anion gap corrected for albumin, phosphate and lactate; SIG - strong ion gap; SIDa - apparent strong ion difference; SIDe - effective strong ion difference. p value for high versus low BE groups. The results are expressed as a number (%), mean or median (IQ) ± standard deviation.