Table 3.
Demographic and treatment-related characteristics of the study population as predictors of reintubation, controlled for gestational age and birth weight
| Variable | Reintubation | p value | |
|---|---|---|---|
| No N (%) | Yes N (%) | ||
| Gestational age | <0.001 | ||
| ≤28 weeks | 8 (4.6) | 11 (17.7) | |
| >28 to ≤32 weeks | 43 (24.9) | 28 (45.2) | |
| >32 to ≤36 weeks | 50 (28.9) | 10 (16.1) | |
| >36 weeks | 72 (41.6) | 13 (21.0) | |
| Weight | 0.003 | ||
| ≤1,000g | 39 (22.3) | 34 (52.3) | |
| >1,000g a ≤1,500g | 45 (25.7) | 14 (21.5) | |
| >1,500g a ≤2,000g | 23 (13.1) | 4 (6.2) | |
| >2,000g a ≤2,500g | 22 (12.6) | 1 (1.5) | |
| >2,500g | 46 (26.3) | 12 (18.5) | |
| Female gender | 89 (50.6) | 43 (66.2) | 0.186 |
| Antenatal corticosteroids | 67 (45.6) | 13 (27.1) | 0.319 |
| Surfactant | 74 (42.0) | 15 (23.1) | 0.547 |
| Postnatal corticosteroids | 167 (94.9) | 55 (86.4) | 0.138 |
| Xanthines | 73 (41.5) | 16 (24.6) | 0.683 |
| 1-minute Apgar | 6.1 (2.5) | 5.4 (2.7) | |
| 5-minute Apgar | 8.0 (1.9) | 7.5 (2.3) | 0.001 |
| MV length (days) | 6.0 (7.5) | 7.9 (7.8) | 0.458 |
| OT brand | 8.5 (1.2) | 8.1 (1.2) | 0.007 |
| Age at extubation | 7.8 (9.0) | 26.7 (17.8) | <0.001 |
| FiO2 | 26.2 (8.6) | 28.9 (9.8) | 0.405 |
| PIP | 14.7 (0.6) | 14.8 (0.7) | 0.384 |
| PEEP | 4.8 (0.5) | 4.8 (0.6) | 0.460 |
| TI | 0.34 (0.03) | 0.33 (0.02) | <0.001 |
| RR | 27.6 (5.1) | 28.7 (5.2) | 0.166 |
| MAP | 7.0 (1.0) | 7.0 (1.2) | 0.869 |
| Flow | 6.96 (0.83) | 6.85 (0.77) | 0.009 |
| PH | 7.42 (0.09) | 7.40 (0.06) | 0.637 |
| PaCO2 | 31.7 (10.6) | 35.2 (9.9) | 0.072 |
| PO2 | 84.4 (46.1) | 67.8 (33.0) | 0.019 |
| StO2 | 90.2 (10.2) | 87.6 (10.0) | 0.374 |
| Bicarbonate | 19.6 (5.0) | 21.4 (5.2) | 0.024 |
| BE | -2.4 (5.5) | -1.7 (4.8) | 0.590 |
MV - mechanical ventilation; OT - orotracheal tube; FiO2 - fraction of inspired oxygen; PIP - peak inspiratory pressure; PEEP - positive end-expiratory pressure; TI - inspiration time; RR - respiratory rate; MAP - mean airway pressure; pH - potential of hydrogen; PaCO2 - partial pressure of carbon dioxide; PO2 - partial pressure of oxygen; StO2 - oxygen saturation; BE - base excess.