Table 4.
Factors that influence HIV/AIDS clinical trial participation according to race, first language and level of education.
| Race (N=1,993)§ | Language (N=2,040)† | Education (N=2,121)† | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| White (N=677) |
African- American (N=871) |
Hispanic (N=445) |
p value* |
English (N=1,748) |
Spanish (N=292) |
p value* |
Elementary (N=153) |
High School (N=678) |
Some College/Technical (N=672) |
College/Graduate (N=618) |
p value* |
|
| Reasons to be in study | ||||||||||||
| Help fight HIV/AIDS | 582 (86%) | 721 (83%) | 320 (72%) | <0.001 | 1,463 (84%) | 204 (70%) | <0.001 | 97 (63%) | 538 (79%) | 578 (86%) | 519 (84%) | <0.001 |
| Better Healthcare | 221 (33%) | 349 (40%) | 215 (48%) | <0.001 | 633 (36%) | 166 (57%) | <0.001 | 67 (44%) | 236 (35%) | 275 (41%) | 251 (41%) | 0.04 |
| Might get money | 212(31%) | 277 (32%) | 102 (23%) | 0.002 | 562 (32%) | 55 (19%) | <0.001 | 36 (24%) | 209 (31%) | 235 (35%) | 151 (24%) | <0.001 |
| Learn about HIV/AIDS | 349 (52%) | 509 (58%) | 235 (53%) | 0.012 | 951 (54%) | 169 (58%) | 0.3 | 84 (55%) | 356 (53%) | 395 (59%) | 319 (52%) | 0.04 |
| Get medications | 211 (31%) | 232 (27%) | 116 (26%) | 0.08 | 494 (28%) | 91 (31%) | 0.3 | 46 (30%) | 166 (24%) | 191 (28%) | 203 (33%) | 0.01 |
| Represent gender | 120 (18%) | 269 (31%) | 116 (26%) | <0.001 | 435 (25%) | 90 (31%) | 0.03 | 52 (34%) | 168 (25%) | 188 (28%) | 125 (20%) | <0.001 |
| Represent race | 71 (10%) | 311 (36%) | 140 (31%) | <0.001 | 429 (25%) | 108 (37%) | <0.001 | 52 (34%) | 176 (26%) | 190 (28%) | 139 (22%) | 0.01 |
| MD recommended | 315 (47%) | 281 (32%) | 150 (34%) | <0.001 | 667 (38%) | 110 (38%) | 0.9 | 57 (37%) | 220 (32%) | 271 (40%) | 247 (40%) | 0.01 |
| Family/friend recommendation | 71 (10%) | 113 (13%) | 45 (10%) | 0.2 | 197 (11%) | 38 (13%) | 0.4 | 25 (16%) | 89 (13%) | 70 (10%) | 59 (10%) | 0.04 |
| Reasons to avoid study | ||||||||||||
| Not friendly to my race | 27 (4%) | 147 (17%) | 44 (10%) | <0.001 | 197 (11%) | 26 (9%) | 0.2 | 9 (6%) | 78 (12%) | 91 (14%) | 55 (9%) | 0.01 |
| Not friendly to my gender | 31 (5%) | 94 (11%) | 30 (7%) | <0.001 | 145 (8%) | 18 (6%) | 0.2 | 5 (3%) | 50 (7%) | 69 (10%) | 43 (7%) | 0.01 |
| Not friendly if I use drugs | 30 (4%) | 102 (12%) | 26 (6%) | <0.001 | 150 (9%) | 17 (6%) | 0.1 | 10 (7%) | 63 (9%) | 63 (9%) | 37 (6%) | 0.07 |
| Not friendly if I use alcohol | 32 (5%) | 74 (8%) | 22 (5%) | 0.004 | 122 (7%) | 17 (6%) | 0.5 | 9 (6%) | 50 (7%) | 53 (8%) | 30 (5%) | 0.1 |
| Worry of being hurt | 147 (22%) | 201 (23%) | 99 (22%) | 0.8 | 407 (23%) | 60 (21%) | 0.3 | 21 (14%) | 142 (21%) | 178 (26%) | 139 (22%) | 0.003 |
| Worry about placebo | 163 (24%) | 96 (11%) | 65 (15%) | <0.001 | 296 (17%) | 41 (14%) | 0.2 | 16 (10%) | 57 (8%) | 125 (19%) | 156 (25%) | <0.001 |
| Worry about confidentiality | 99 (15%) | 195 (22%) | 80 (18%) | <0.001 | 330 (19%) | 53 (18%) | 0.7 | 21 (14%) | 110 (16%) | 137 (20%) | 135 (22%) | 0.02 |
| Worry medications will not work/hurt me | 226 (33%) | 273 (31%) | 127 (29%) | 0.2 | 564 (32%) | 86 (29%) | 0.3 | 37 (24%) | 174 (26%) | 252 (38%) | 208 (34%) | <0.001 |
| Do not understand the studies | 26 (4%) | 91 (10%) | 40 (9%) | <0.001 | 132 (29%) | 29 (10%) | 0.2 | 10 (7%) | 78 (12%) | 57 (8%) | 20 (3%) | <0.001 |
| Do not have time | 115 (17%) | 126 (14%) | 71 (16%) | 0.4 | 275 (16%) | 40 (14%) | 0.4 | 18 (12%) | 103 (15%) | 87 (13%) | 120 (19%) | 0.01 |
| Do not want to be “guinea pig” | 43 (6%) | 133 (15%) | 43 (10%) | <0.001 | 211 (12%) | 26 (9%) | 0.1 | 18 (12%) | 81 (12%) | 88 (13%) | 53 (9%) | 0.07 |
*
Chi-Square Test.
§
Excluded individuals who responded other race (N=102), mixed race (N=23) or had no response (N=57).
†
Excluded individuals who responded other language (N=31) or had no response (N=104).
‡
Excluded individuals who had no response (N=54).