Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pharmacokinetic profile of rohitukine after oral (50 mg/kg) and intravenous (5 mg/kg) administration (n = 3)
| Estimates (mean ± SD) | ||
| Parameters | Oral (50 mg/kg) | Intravenous (5 mg/kg) |
| Cmax (µg/ml) | 6.62 ± 0.66 | 5.37 ± 2.12 |
| Tmax (h) | 0.25 | — |
| AUC0–∞ (µg * h/ml) | 10.66 ± 2.34 | 4.14 ± 1.08 |
| MRT (h) | 6.64 ± 1.39 | 7.07 ± 3.02 |
| Fabs (%) | 25.7 | — |
AUC, area under the curve from 0 to ∞ h; Cmax, maximum concentration; Fabs, absolute bioavailability; MRT, mean residence time; Tmax, time of maximum concentration.
