Table 1.
Etiology | An examplea | A mechanisma |
---|---|---|
Tumorigenic | Iris melanoma | Tumor seeding drainage angle |
Traumatic | Angle recession | Direct angle contusion |
Infectious | Herpes simplex | Trabeculitis |
Inflammatory | Juvenile idiopathic arthritis | Scarring and inflammation in the outflow pathway |
Degenerative | Primary open angle glaucoma | Multifactorial |
Developmental | Congenital glaucoma | Incomplete angle development |
Vascular | Neovascular glaucoma after diabetic retinopathy | Reduced outflow triggered by vascular endothelial growth factor diffusion into the anterior segment |
aThere are many examples and more than one mechanism involved in each etiological category.