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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Biomaterials. 2014 Mar 21;35(18):4996–5005. doi: 10.1016/j.biomaterials.2014.03.007

Fig. 6.

Fig. 6

Calculated free energy of interaction of PEGylated CL–DNA complexes with the cell’s plasma membrane as a function of distance. Steric repulsion gives rise to a repulsive barrier, but a global minimum representative of adhesion appears at sufficiently high membrane charge density. Low and high σM refers to DOTAP/DOPC/PEG2K-lipid–DNA NPs with lipid molar ratios of 30/60/10 and 80/10/10, respectively.