Table 3.

Uni- and multi-variate analyses for prognostic factors in CRC patients

	Univariate			Multivariate
Variables	HR$	95%CI	p value	HR$	95%CI	p value
Age (≥ 67 vs. <67)	0.76	0.42–1.35	0.35	-	-	-
Gender (Female vs. Male)	1.02	0.56–1.86	0.92	-	-	-
Pathological T stage (T3/4 vs.1/2)	8.97	2.19–36.7	0.0024	3.63	0.82–16.1	0.091
Pathology (poor vs. mod/well differentiated)	2.26	1.05–4.84	0.036	2.07	0.86–4.96	0.105
Lymph node metastasis (positive vs. negative)	17.1	6.18–47.8	< 0.0001	1.24	0.28–5.46	0.78
TNM stage (III/IV vs. I/II)	33.4	8.12–136.9	< 0.0001	10.2	1.27–81.7	0.03
CEA (≥ 5 vs. <5)	4.84	2.15–10.89	0.0001	1.46	0.57–3.74	0.43
miR-200c in serum (high vs. low)	2.43	1.26–4.68	0.006	2.67	1.28–5.67	0.01
miR-200c in primary tumor (high vs. low)	0.56	0.28–1.10	0.092	-	-	-

HR, Hazard ratio; CI, Confidence interval; CEA, Carcinoembryonic antigen; mod, moderately; TNM, tumor-node-metastasis staging

^$HR, hazard ratio for survival outcome in CRC patients