Figure 3. Immunohistochemical Analysis of Transporter Gene Expression in the Cornea.
Control cornea sections were prepared with hematoxylin-eosin (H & E) staining (A) to differentiate the tissue layers (epithelium and stroma are labeled). Protein expression pattern of four transporters was evaluated by IHC: BCRP (B), OCT3 (C), MRP4 (D), and OAT2 (E). In (C) the arrow (↑) denotes the corneal endothelium. Scale bars are set to 20 microns. Data are from three orbs obtained from two individuals, see Supplemental Table S1 for donor information. An eye pathologist reviewed all IHC of the cornea.