Ranking of NK1 receptor immunoreactivity at 10(A), within the injury epicentre (B) and at 10 mm caudal (C). At 24 hours post-SCI a significant increase was observed within the injury epicentre (E = vehicle and F = NAT), whilst adjacent segments demonstrated a slight increase (G = vehicle and H = NAT). By 2 weeks post-SCI tissue loss was too great to assess NK1 immunoreactivity within the injury epicentre (I-vehicle, J-NAT) although adjacent segments had reduced immunoreactivity (K-vehicle, L-NAT). No differences were observed between treatment groups at any time point. *denotes p<0.05, **denotes p<0.01, ***denotes p<0.001, sham median ranking indicated by the dashed line (A,B & C). Scale bar = 1 mm.