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. 2014 May 23;9(5):e98041. doi: 10.1371/journal.pone.0098041

Figure 1. FBI-1 enhances transcriptional activity of ETS-1.

Figure 1

(A-D) Lovo cells were transfected with ETS-RE-Luc reporter. (A, C-D) Cells were stably transfected with FBI-1 expression vector or empty vector. (B) Cells were transfected with FBI-1 siRNA or control siRNA. (D) Cells were transfected with ETS-1 siRNA (D). Lovo cells were treated with 5 ng/ml HGF (A-D, F), or ARQ-197 (C). (E) Overexpression or knockdown of FBI-1 were examined by western blot. The luciferase values are the mean ± SE of three independent experiments with similar results. *P<0.05 versus with the empty vector or the FBI-1 vector (A-D); versus with the control siRNA or the FBI-1 siRNA (A-D); versus with or without HGF/ARQ-197.