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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Epilepsia. 2013 May 29;54(7):1240–1250. doi: 10.1111/epi.12223

Figure 5.

Figure 5

PET-based ROI analysis of functional changes after LFPI found no significant differences between epileptic and non-epileptic rats. However, a multivariate logistic regression model that incorporated the one week, one month, and three month PET parameters from the ipsilateral hippocampus was able to predict the epileptic outcome in all of the LFPI cases. Time course of metabolic changes on PET scans in the hippocampus (A) and the cortex (B) are shown (mean ± SEM). Representative PET images at three months post-injury demonstrate a decrease in metabolism in both the LFPI groups (epileptic - C and non-epileptic - D) relative to sham-injury (E; see Liu et al., 2010 for additional details), with worsened hypometabolism observed in the ipsilateral hippocampus of the epileptic group.