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. Author manuscript; available in PMC: 2015 Sep 15.
Published in final edited form as: Biol Psychiatry. 2013 Nov 23;76(6):447–455. doi: 10.1016/j.biopsych.2013.11.018

Table 3.

Descriptive and comparative statistics for Local Gyrification Index (LGI) in regions of significant and trending proband hypogyria

Large Region Region Mean LGI (SE)a Effect sizes for contrasts to controls Cohen's d
Controls (HC) n=243 All Relatives (Rel) n=300 Axis IIA Relatives (AxIIA) n=33 Probands (Prob) n=388
HC-Rel HC-AxIIA HC-Prob
Cingulate Left Caudal Anterior Cingulate 1.73 (0.01) 1.72 (0.01) 1.70 (0.02) 1.71 (0.01) 0.087 0.221 0.175**
Left Posterior Cingulate 1.77 (0.01) 1.76 (0.01) 1.76 (0.02) 1.74 (0.01) 0.017 0.074 0.146$
Right Caudal Anterior Cingulate 1.78 (0.01) 1.78 (0.01) 1.77 (0.02) 1.76 (0.01) 0.022 0.155 0.187**
Right Posterior Cingulate 1.81 (0.01) 1.82 (0.01) 1.80 (0.02) 1.79 (0.01) −0.010 0.146 0.179*
Composite 1.78 (0.01) 1.78 (0.01) 1.76 (0.02) 1.76 (0.01) 0.020 0.247$ 0.130*
a

Values adjusted for age, sex, site, race, lithium usage, and intracranial volume

$

p < 0.06

*

p<0.05

**

p<0.01

*** p<0.001 (All p-values reflect Benjamini-Hochberg adjustment)