Table 1.

Patient tumor deformation measurements.

Deformation type	Tumor site	Magnitude	Imaging method	No. of patients	Reference
Single tumor deformation	Lung	max >10 mm	4DCT	6	Kyriakou and McKenzie (Ref. 16)
		max 2.7 mm	4DCT	10	Liu et al. (Ref. 17)
	Pancreas	up to 5 mm	Cine-MRI	17	Feng et al. (Ref. 18)
	Prostate	<1 mm	Calypso	11	Burch et al. (Ref. 19)
			Cine-MRI	6	Ghilezan et al. (Ref. 20)
Tumor system deformation	Lung – lymph node	Nodes max >10 mm and uncorrelated primary-nodes motion	4DCT	20	Donnelly et al. (Ref. 22)
			4DCT	41	Pantarotto et al. (Ref. 23)
	Prostate – lymph node	max >10 mm for 1.3% of time	Calypso	17	Langen et al. (Ref. 24)
		max >15 mm	kV images	10	Ng et al. (Ref. 25)