Table 1.
Frequency distribution of the C34T AMPD1 alleles and genotypes
| Individuals | Group size (n) |
Allele frequencies (%) |
p-value compared with control |
AMPD1
C34T genotype frequencies (%) |
P-value HWE | P-value compared with control | |||
|---|---|---|---|---|---|---|---|---|---|
| C | T | CC | CT | TT | |||||
| Endurance group |
84 |
86.9 |
13.1 |
0.603 |
62 (72.9)* |
22 (25.9)* |
0* |
0.167 |
0.359 |
| Sprint and power group |
47 |
95.7♦ |
4.3♦ |
0.039 |
43 (86.3)*♣ |
4 (11.8)*♣ |
0*♣ |
0.761 |
0.010 |
| Mixed group |
73 |
83.6♦ |
16.4♦ |
0.999 |
49 (67.1) |
24 (32.9)♣ |
0♣ |
0.092 |
0.216 |
| Total athletes |
204 |
87.7 |
12.3 |
0.287 |
154 (74.2) |
50 (24.9) |
0 |
0.050 |
0.025 |
| Control subjects | 260 | 84.0 | 16.0 | - | 185 (72.2) | 67 (25.5) | 8 (2.4) | 0.525 | - |
*χ2 = 5.62, d.f. = 2, P = 0.021 for AMPD1 genotype frequencies in endurance athletes versus sprint/power athletes.
♣χ2 = 9.09, d.f. = 2, P = 0.002 for AMPD1 genotype frequencies in sprint / power athletes versus mixed athletes.
♦χ2 = 6.32; df = 1; P = 0.004 for AMPD1 alleles frequencies in sprint / power athletes versus mixed athletes.
Significant mean differences (P < 0.05) are in bold.