Table 5.
Secondary endpoints - pain over the last 24 hours and global patient assessment on disease activity evaluated at each visit on a VAS (100 mm)
| N | Pain (VAS) | P value | Disease activity | P value | |
|---|---|---|---|---|---|
| V1 |
22 |
49.41 ± 24.94 |
ns |
60.00 ± 22.67 |
ns |
| V2 |
22 |
50.95 ± 23.85 |
ns |
58.32 ± 20.37 |
ns |
| V3 |
21 |
44.52 ± 27.41 |
ns |
48.71 ± 27.37 |
ns |
| V4 |
20 |
42.20 ± 26.33 |
ns |
42.70 ± 25.82 |
ns |
| V5 | 20 | 39.20 ± 28.96 | ns | 38.85 ± 27.66 | 0.0047* |
*p value versus V1. Data are mean ± sd and were analyzed with Student t-test. V1: first visit, at the time of selection; V2: visit after 7 days of treatment; V3: visit after 14 days of treatment; V4: visit after 28 days of treatment; V5: visit after 84 days of treatment.