Figure 5.

RECQL5 Depletion Results in Chromosomal Instability

(A) Left: outline of CGH approach. Right: gains or losses of genomic regions upon RECQL5 depletion and in WT cells.

(B) Example of gene-rich region on chromosome 7p13, lost upon RECQL5 depletion. Each black dot represents a different probe on the microarray and the red lines their mean. Expanded area depicts only some of the annotated transcripts in the lost region.

(C) Recurrent lost regions and their correlation with transcription, as well as CFSs.

(D) As in (C), but for regions of gain. See also Tables S2, S3, and S4.